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(A) Representative electron microscopy images of collagen fibrils, extracted from femoral bones of fl/fl Cre+ mice and control littermates, are shown from paired samples. (B and C) Quantification of the diameters of collagen fibrils are shown from two littermate pairs of control and mutant mice. 87–158 individual fibrils were measured in 30–37 separate image fields from each bone.
