Table 2.
Spearman Correlations; r,p With Body Composition and Bone Biopsy Measures In 25 IOP women
| %COP | IGF-1R MFI | CTX | PINP | Serum IGF-1 | |
|---|---|---|---|---|---|
|
| |||||
| Age | −0.11, 0.6 | 0.15, 0.5 | −0.30, 0.2 | −0.17, 0.4 | −0.60, 0.003 |
|
| |||||
| BMI | −0.23, 0.3 | −0.30, 0.1 | −0.03, 0.9 | 0.11, 0.6 | −0.22, 0.3 |
|
| |||||
| Whole body fat by DXA | −0.18, 0.4 | −0.44, 0.03 | −0.44, 0.04 | −0.11, 0.6 | −0.18, 0.4 |
|
| |||||
| Trunk fat by DXA | −0.26, 0.2 | −0.42, 0.04 | −0.39, 0.07 | −0.07, 0.8 | −0.18, 0.42 |
|
| |||||
| BMD by DXA (g/cm2) | |||||
| Lumbar Spine | −0.31, 0.14 | −0.40, 0.05 | −0.08, 0.7 | 0.17, 0.4 | −0.31, 0.2 |
| Total Hip | 0.07, 0.7 | −0.23, 0.3 | 0.16, 0.5 | 0.04, 0.9 | 0.15, 0.5 |
| Femoral Neck | −0.07, 0.7 | −0.22, 0.3 | 0.16, 0.5 | 0.14, 0.5 | 0.10, 0.65 |
|
| |||||
| Transiliac Crest Bone Biopsies: | |||||
|
| |||||
| BV/TV | 0.34, 0.10 | 0.38, 0.06 | 0.28, 0.2 | −0.16, 0.5 | −0.08, 0.7 |
|
| |||||
| Cancellous Wall Width (μm) | 0.51, 0.01 | 0.16, 0.4 | 0.10, 0.7 | −0.17, 0.4 | −0.05, 0.8 |
|
| |||||
| Mineralized Perimeter (%) | 0.21, 0.3 | 0.62, 0.0009 | 0.38, 0.08 | 0.13, 0.5 | −0.24, 0.3 |
|
| |||||
| Mineral Apposition Rate (MAR: μm/day) | 0.75, <0.0001 | 0.21, 0.3 | 0.27, 0.22 | 0.01, 0.9 | −0.05, 0.8 |
|
| |||||
| Bone Formation Rate (BFR: mm2/mm/yr) | 0.41, 0.04 | 0.57, 0.003 | 0.43, 0.05 | 0.08, 0.7 | −0.09, 0.7 |
|
| |||||
| Osteoblast Number (#/mm) | 0.01, 0.9 | 0.28, 0.2 | −0.02, 0.9 | 0.01, 0.9 | −0.37, 0.09 |