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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: J Orthop Res. 2017 Jan 15;35(9):1876–1885. doi: 10.1002/jor.23502

Figure 3. Elevated number of fibrogenic/adipogenic progenitor (FAP) cells in the muscle following an ACL injury.

Figure 3

(A–B) Representative immunohistochemical images demonstrating PDGFRα+ FAPs (white arrowheads, red), muscle connective tissue (green), and DAPI (blue) in the non-injured (A) and injured (B) limb skeletal muscle. Scale bar = 50µm. (C) Quantification of PDGFRα+ FAPs presented as mean number of FAPs per muscle area (mm2) ± SEM. (D) Correlation of the number of FAPs per mm2 with percent area of muscle connective tissue in the injured limb. N = 9 subjects. NI = non-injured; I = injured. * Significantly different from the non-injured limb (p < 0.05).