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NAP Tissue Concentrations in CD-1 Mice
(A) Distribution of NAPs in different tissues 6 hr after the first i.v. bolus injection (96 mg/kg). (B) NAP concentrations in kidney and liver with chronic dosing. Plotted values = mean ± SD (n = 4 [2 male/2 female]). Asterisks (*) indicate statistically significant difference between REP 2139 and REP 2165 (p < 0.05) at equivalent dose as determined by t test. ND, not determined.
