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. 2017 Jun 9;7:3175. doi: 10.1038/s41598-017-03580-5

Table 1.

Characteristics of Patients.

Variable n CDS + RT (%) CDS (%) P value
(n = 4059) (n = 4298)
Age <0.001
 <50 5697 2558 (63.0) 3139 (73.0)
 ≥50 2660 1501 (37.0) 1159 (27.0)
Race 0.072
 White 6587 3166 (78.0) 3421 (79.6)
 Black 775 406 (10.0) 369 (8.6)
 Other 995 487 (12.0) 508 (11.8)
Marital status 0.138
 Single 2121 1008 (24.8) 1113 (25.9)
 Married 6236 3051 (75.2) 3185 (74.1)
Histologic type <0.001
 Squamous cell carcinoma 5137 2673 (65.9) 2464 (57.3)
 Adenocarcinoma 1363 508 (12.5) 855 (19.9)
 Adenosquamous carcinoma 565 301 (7.4) 264 (6.1)
 Others 1292 577 (14.2) 715 (16.6)
Primary site 0.001
 Cervix uteri 5840 2917 (71.9) 2923 (68.0)
 Endocervix 1986 899 (22.1) 1087 (25.3)
 Exocervix 236 101 (2.5) 135 (3.1)
 Overlapping lesion of cervix uteri 295 142 (3.5) 153 (3.6)
Grade <0.001
 I 1061 330 (8.1) 731 (17.0)
 II 3539 1612 (39.7) 1927 (44.8)
 III 3513 1969 (48.5) 1544 (35.9)
 IV 244 148 (3.6) 96 (2.2)
FIGO <0.001
 IB 6577 2561 (63.1) 4016 (93.4)
 IIA 391 299 (7.4) 92 (2.1)
 IIB 1389 1199 (29.5) 190 (4.4)
Nodal status <0.001
 Node negative 6586 2533 (62.4) 4053 (94.3)
 Node positive 1771 1526 (37.6) 245 (5.7)
Size <0.001
 ≤2 cm 3350 929 (22.9) 2421 (56.3)
 2–4 cm 3044 1637 (40.3) 1407 (32.7)
 >4 cm 1963 1493 (36.8) 470 (11.0)
Surgical method <0.001
 Local tumor destruction 800 582 (14.3) 218 (5.1)
 Hysterectomy 7472 3403 (83.8) 4069 (94.7)
 Pelvic exenteration 85 74 (1.8) 11 (0.3)

CDS: cancer-directed surgery; RT: radiotherapy; FIGO: International Federation of Gynecology and Obstetrics.