Table 1.

The feasibility of drVM in various types of clinical samples and public datasets

				drVM result (No. of run)
Study description	Sequencing method	No. of runs	Ref	Detection	Reconstruction
Bioinformatics pipeline for ultrarapid pathogen identification	Illumina	13	[10]	6	0
Complete viral RNA genome sequencing of ultra-low copy samples	Illumina	34	[19]	9	25
Faecal virome of red foxes from peri-urban areas	Illumina	8	[28]	0	1
Full genome virus detection in fecal samples	Illumina	20	[20]	0	11
Human papillomavirus community in healthy persons	Illumina	20a	[21]	9	5
Identification of hepatotropic viruses from plasma	Illumina	14	[18]	1	4
Intestinal bacterial and RNA viral communities from sentinel birds	Ion Torrent	8	[24]	7	0
Intestinal virome in healthy and diarrhoeic neonatal piglets	Ion Torrent	29	[27]	3	2
Metagenomic analysis for severe acute respiratory infection	Illumina	4	[29]	0	4
Metagenomic identification of viral pathogens in clinical samples	Illumina	3	[25]	1	1
New viral sequences identified in Asian citrus psyllid	Illumina	4	[26]	1	3
Novel adenovirus associated with baboon acute respiratory outbreak	Illumina	4	[17]	3	1
Novel human pegivirus associated with hepatitis C virus co-infection	Illumina	15	[23]	11	2
RNA sequencing in influenza virus-positive respiratory samples	Illumina	49	[9]	16	13
RNA-seq of RNA viruses from faecal and blood samples	Illumina	82	[8]	6	76
Simultaneous sequencing of multiple RNA virus genomes	Ion Torrent	40	[22]	33	4
Viral genome-targeted assembly pipeline	Illumina	1	[13]	1	0
Virus identification in unknown tropical febrile illness cases	Illumina	1b	[16]	1	0

^aSelected runs with assembled contigs >1000 bp [21].

^bA selected run with mapped viral reads >5000 [16].