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. 2017 Jan 7;6(2):1–11. doi: 10.1093/gigascience/giw015

Figure 1:

Figure 1:

Estimation of the total number of phosphoproteins (1A, 1B) and p-sites (1C, 1D) for yeast, with the curve-fitting (assuming 1 % noise) and Capture-Recapture methods, also correcting for three levels of noise (1 %, 5 %, 10 %). In Fig. 1A and C, the x-axis is the cumulative number of redundant phosphoproteins/p-sites, whereas the y-axis is the cumulative number of non-redundant phosphoproteins/p-sites. The red curve is fitted for 1 % noise. In Fig. 1B and D: Current is the total number of phosphoproteins/p-sites detected so far (by applying our filtering criteria). Current_3X is the total number of phosphoproteins/p-sites detected so far in at least three experiments. Rcapture is the estimation of maximum number of phosphoproteins/p-sites based on the Rcapture method (using the 15 largest datasets). Rcapture_HTP_vs_LTP is the estimation of maximum number of phosphoproteins/p-sites based on the Rcapture method, but this time using only two datasets, where one of them is the compendium of all HTP experiments and the second is the compendium of all LTP experiments from PhosphoGrid2. CF is the estimation of maximum number of phosphoproteins/p-sites based on the curve-fitting method of the saturation curve from all experiments. CF_3X is the estimation of maximum number of phosphoproteins/p-sites identified in at least three experiments, based on the curve-fitting method (in this case, a reasonable estimate was not possible). CF_best_start is the estimation of maximum number of phosphoproteins/p-sites based on the curve-fitting method of the saturation curve from all experiments, but this time, the largest experiment is used as first in the series. CF_best_end is the estimation of maximum number of phosphoproteins/p-sites based on the curve-fitting method of the saturation curve from all experiments, but this time, the largest experiment is used as last in the series. CF_half_exp is the estimation of maximum number of phosphoproteins/p-sites based on the curve-fitting method of the saturation curve from the first half experiments.