Fig. 1.

Using a rat model of VML, we tested the hypothesis that bone marrow mononuclear cells (BMNCs) directly contribute to de novo muscle fiber regeneration, by transplanting MG in a collagen carrier at a dose of 50% of the VML injury both with and without concomitant delivery of 5 million BMNCs derived via density gradient centrifugation from the bone marrow of a syngeneic greens fluorescent protein (GFP)⁺ donor. RBC red blood cell