Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Compound 4 is selective for p97. (A–C) HEK293 cells were treated with indicated concentrations of curvularins for 24 h. (A) Total ubiquitin, (B) TCRα-GFP (green fluorescent protein) and (C) hemagglutinin (HA)-CD3δ were analyzed by immunoblot. The negative (−) and positive (+) controls used were DMSO and MG132 (a proteasome inhibitor), respectively. Loading controls are β-actin and GAPDH.
