Skip to main content
. 2017 Jun 12;8:681. doi: 10.3389/fimmu.2017.00681

Figure 5.

Figure 5

Effects of heparanase or heparan sulfate on serum heparanase activity and serum heparan sulfate levels in C57BL/6J mice. (A) Heparan sulfate degradation activity and (B) heparan sulfate levels were assessed 24 h subsequent to either vehicle (sham), heparanase (1 U i.v.; Hep), or heparan sulfate (1 mg i.v.; HS) administration in 2-month-old male C57BL/6J mice. The following groups were studied: C57BL/6J vehicle (n = 8); C57BL/6J heparanase (n = 8); C57BL/6J heparan sulfate (n = 8). Data are expressed as means ± SEM for n number of observations. *p < 0.05 vs. C57BL/6J vehicle (Kruskal–Wallis test with Dunn’s multiple comparisons test).