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Anti-Paracoccidioides activity and quantitative analysis of dodecyl and amphotericin B (AMB) incorporated into the NLS.
| Pb18 MIC | Pb01 MIC | Pb02 MIC | |
|---|---|---|---|
| (μg/mL) | (μg/mL) | (μg/mL) | |
| Dodecyl | 0.48 | 0.48 | 0.24 |
| NLS+dodecyl | 0.03 | 0.03 | 0.06 |
| X increase | 16 | 16 | 4 |
| AMB | 0.13 | 0.06 | 0.12 |
MFC = MIC; Pb18, P. brasiliensis 18; Pb01, P. lutzii 01; Pb02, P. brasiliensis 02; MIC90, (90% minimum inhibitory concentration)..
