Table 5.
Summary of IL-10 subarachnoid hemorrhage clinical studies.
| Study modality | Population | Outcomes | Reference |
|---|---|---|---|
| – | Austrian | Mean blood IL-10 levels low throughout ICU stay | (114) |
| ELISA | Swedish | Microdialysate IL-10 present at low levels and remained constant through 7 days post-bleed | (115) |
| ELISA | British | Plasma and CSF IL-10 levels constant through 10 days post-bleed, plasma and CSF levels equal | (116) |
| PCR | American | IL-10 mRNA not found in aneurysm walls, but was present in temporal artery controls | (117) |
| TaqMan Allelic Assay | Indian | IL-10 SNPs rs1800871 and 1800872 associated with intracranial aneurysm incidence, no correlation with rupture | (118) |
ICU, intensive care unit; PCR, polymerase chain reaction; SNP, single nucleotide polymorphism; IL-10, interleukin-10.