Table 7.
Summary of IL-10 intracerebral hemorrhage clinical studies.
| Study modality | Population | Outcomes | Reference |
|---|---|---|---|
| ELISA | Japanese | Higher plasma IL-10 levels in ICH patients with poor 1 month old mRS outcomes | (124) |
| ELISA | Taiwanese | Higher plasma IL-10 level on admission associated with hematoma expansion and worse 1 month old outcome | (119) |
| ELISA | Polish | Admission IL-10 levels negatively correlate with GCS, IL-10 correlates with IL-6 levels | (125) |
| ELISA | Polish | Systemic IL-10 at 2 days is higher in left hemisphere hemorrhages compared to right hemisphere hemorrhages | (126) |
| ELISPOT | Swedish | IL-10-secreting MNCs are elevated compared to healthy controls | (84) |
ELISA, enzyme-linked immunosorbent assay; ELISPOT, enzyme-linked immunospot assay; GCS, Glasgow Coma Scale; HPLC, high-performance liquid chromatography; MNCs, mononuclear cells; mRS, modified Rankin scale; IL-10, interleukin-10.