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. 2017 Jun 12;4:84. doi: 10.3389/fvets.2017.00084

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Copyright © 2017 Berglund, Fisher, Cameron, Poole and Schnabel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Major histocompatibility complex (MHC) I and MHC II surface expression kinetics on untreated and transforming growth factor-β2 (TGF-β2)-pretreated mesenchymal stem cells (MSCs) following IFN-γ stimulation. MHC I and MHC II expression were measured on untreated and TGF-β2-pretreated MSCs from two horses via FACS every 24 h for 72 h following IFN-γ stimulation. (A) MHC I expression shown as the geometric mean fluorescence intensity (GMFI) of MSCs in each treatment group over time. (B) MHC II expression shown as the percent of the parent MSC population positive for MHC II in each treatment group over time.