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. 2017 Jun 12;4:84. doi: 10.3389/fvets.2017.00084

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Copyright © 2017 Berglund, Fisher, Cameron, Poole and Schnabel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Production of TGF-β1 and transforming growth factor-β2 (TGF-β2) by untreated and TGF-β2-treated mesenchymal stem cells (MSCs). TGF-β1 and TGF-β2 concentrations were measured in the supernatant of untreated (−/− TGF-β2), untreated and IFN-γ stimulated (−/− TGF-β2 + IFN-γ), TGF-β2-pretreated (+/− TGF-β2), and TGF-β2-pretreated and IFN-γ stimulated (+/− TGF-β2 + IFN-γ) MSCs using a TGF-β multiplex assay. Superscript letters indicate significant differences between groups. (A) TGF-β1 is displayed as the mean concentration ± SD of n = 7. (B) TGF-β2 is displayed as the mean concentration ± SD of n = 7, p = 0.0045 by analysis of covariance.