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. 2017 Jun 12;8:279. doi: 10.3389/fphar.2017.00279

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Copyright © 2017 Ferris, Kulkarni, Yee, Nedelman and de Jong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Two dimensional activation maps of the septo-hippocampal system. 2D activation maps from the rat brain atlas showing the precise location of the significantly altered positive (red) voxels for each of the experimental conditions taken from the 25 to 35 min post-treatment time window in the septo-hippocampal system. The figures on the right show the localization of the voxels on the original neuroanatomical images for the combined donepezil/idalopirdine condition. The vertical color strip indicates the percent change in BOLD signal. IDL, idalopirdine; DPZ, donepezil.