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. 2017 Mar 15;6(5):1–11. doi: 10.1093/gigascience/gix017

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© The Author 2017. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5: — Pan-cancer neoantigens. (a) The flow-char of neoantigen prediction pipeline. Software with parameters using in the pipeline are shown in dashed line. (b) The distribution of neoantigens generated from each SNV across diverse cancers. (c) The distribution of neoantigens generated from each InDel across diverse cancers. (d) The distribution of neoantigen loads across 10 cancer types. The cancer types are sorted by median value of neoantigen loads. (e) The expression of HLA class I in tumor and corresponding normal samples.