Table 3.
Comparison of major serum and urinary metabolites responsible for the separation between two groups of ulcerative colitis patients12
|
UC groups |
VIP score | Fold change (remission/relapse) | P value3 | ||
| Remission | Relapse | ||||
| Trans-aconitate (urine) | 0.5 (0.5-1.6) | 3.6 (1.9-5.5) | 1.9 | 0.2 | 0.02 |
| 3-hydroxybutyrate (serum) | 21.0 (15.0-33.9) | 127.8 (37.5-232.0) | 1.4 | 0.2 | < 0.01 |
| Cystine (urine) | 5.3 (4.0-8.6) | 3.3 (1.4-5.9) | 1.4 | 2.7 | 0.07 |
| Acetamide (urine) | 4.9 (2.7-7.1) | 2.6 (0.8-3.8) | 1.3 | 2.4 | 0.05 |
| Acetoacetate (serum) | 7.8 (5.8-13.0) | 25.6 (10.5-60.2) | 1.2 | 0.3 | 0.02 |
| Acetone (serum) | 5.3 (4.2-8.7) | 11.9 (6.0-24.7) | 1.1 | 0.4 | 0.06 |
1
Concentrations are presented as median (interquartile range);
2
Unit of concentration for the metabolites in serum and urine is μmol and μmol/mmol, respectively;
3
Obtained from Mann-Whitney U test.