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Protumorigenic role of NOS2 and NOS3 based on the studies involving genetically engineered mouse model of pancreatic cancer with pancreas-specific mutation in the Kras and P53 genes. eNOS/NOS3, endothelial nitric oxide synthase; iNOS/NOS2, inducible nitric oxide synthase. To see this illustration in color, the reader is referred to the web version of this article at www.liebertpub.com/ars
