Figure 4. MS repeats recurrently altered by MSI in MSI-H tumours.

(a) The barplots report the number of COAD, STAD and UCEC tumours harbouring MSI events at the loci indicated in the central panel. This analysis examined 190 MSI-H, 118 MSI-L and 522 MSS exomes. (b) The recurrence analysis was extended to 25 MSI-H, 19 MSI-L and 105 MSS whole genomes. Genomic coordinates in a,b indicate the location of the MSI repeats in the hg19 assembly of the human genome.