Scheme 1. Synthesis of Tracer 5.
Reagents and conditions: (a) (Boc)2O, THF, 23 °C, 20 h; (b) THF, 65 °C, 20 h; (c) Hydrazine, THF, 70 °C, 2 h; (d) Py, 18 h; (e) THF, TFA, 50 °C, 3 h; (f) Fluorescein-NCS, DIPEA, DMF, 23 °C, 1 h.
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