Figure 3. Lithium chloride ameliorates the depressive-like state.

(a) Overnight treatment with a 50 mM LiCl water solution induces excessive climbing attempts at the 4.5 mm gap in stressed and control flies. (b) At the lower concentration of 5 mM control flies show the same motivation to climb (Test 2) as in the pre-test. Vibration-treated flies recover from the depressive-like state (Test 1 versus Test 2) and show a similar motivation to climb as in the pre-test. Black squares, medians; boxes, 25 and 75% quartiles; whiskers, 10 and 90% quantiles; numbers of animals are indicated below each box; NS, not significant; **, P<0.01; Kruskal–Wallis test.