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. 2017 Jun 12;36:78. doi: 10.1186/s13046-017-0548-7

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — ANGPTL1 represses migration and invasion of CRC cells in vitro. a SW620-ANGPTL1 cells exhibited significantly reduced mobility compared to vector control cells (P < 0.0001). b Invasion assay indicated that SW620-ANGPTL1 cells had significantly reduced invasion capacity compared to SW620-Ctrl cells (P < 0.0001). c-d The number of invading cells was significantly higher in the SW480-shANGPTL1 cells compared to that in the SW480-Ctrl cells by transwell migration (P < 0.0001) (c) and invasion assay (P = 0.0159) (d)