Table 1.

ANGPTL1 expression was significantly down regulated in cancer tissues of 14 cancer types

Cancer Type	Numbera	Normalb	Cancerb	log2FoldChangec	Adjusted P valued
BLCA	19	637.89	25.25	−4.66	<0.0001
BRCA	113	600.86	74.84	−3.01	<0.0001
CHOL	9	427.26	107.93	−1.98	<0.0001
CRC	32	797.1	38.74	−4.36	<0.0001
ESCA	11	816.82	40.15	−4.35	0.04
HNSC	43	418.62	31.68	−3.72	<0.0001
KIRC	72	529.9	63.99	−3.05	<0.0001
KIRP	72	439.06	80.07	−2.46	<0.0001
LUAD	58	300.09	44.4	−2.76	<0.0001
LUSC	51	309.17	27.88	−3.47	<0.0001
PRAD	52	287.12	81.15	−1.82	<0.0001
STAD	32	1520.86	154.21	−3.3	<0.0001
THCA	59	1423.74	382.68	−1.9	<0.0001
UCEC	7	1267.48	87.89	−3.85	<0.0001

Abbreviations: BLCA bladder urothelial carcinoma, BRCA breast invasive carcinoma, CHOL cholangiocarcinoma, CRC colorectal cancer, ESCA esophageal carcinoma, HNSC head and neck squamous cell carcinoma, KIRC kidney renal clear cell carcinoma, KIRP kidney renal papillary cell carcinoma, LUAD lung adenocarcinoma, LUSC lung squamous cell carcinoma, PRAD prostate adenocarcinoma, STAD stomach adenocarcinoma, THCA thyroid carcinoma, UCEC uterine corpus endometrial carcinoma

^aNumber of paired normal and cancer tissues included in this study. We only considered the cancer type with six or more samples for differential expression analysis

^bMean expression level of normal or cancer tissue

^cFold change is calculated by mean expression level of Cancer/Normal

^d P value was performed by DEGSeq package for R/Bioconductor and adjusted P value was counducted according to false discovery rate