Table 2.
Univariate survival analysis of OS and DFS in 110 patients with colorectal cancer.
| Characteristics | DFS | OS | ||||
|---|---|---|---|---|---|---|
| Mean ± SE (months) | 95% CI | P a | Mean ± SE (months) | 95% CI | P a | |
| Age (years) | 0.421 | 0.332 | ||||
| <60 | 43.79 ± 2.57 | 38.75–48.84 | 44.50 ± 2.50 | 39.60–49.40 | ||
| ≥60 | 48.05 ± 2.20 | 43.74–52.36 | 49.50 ± 2.07 | 45.45–53.55 | ||
| Sex | 0.931 | 0.808 | ||||
| Male | 45.01 ± 2.52 | 40.07–49.94 | 45.91 ± 2.43 | 41.14–50.68 | ||
| Female | 46.71 ± 2.32 | 42.17–51.25 | 47.94 ± 2.21 | 43.60–52.27 | ||
| Tumor size | 0.597 | 0.495 | ||||
| <5 cm | 46.93 ± 2.64 | 41.76–52.09 | 47.76 ± 2.56 | 42.75–52.77 | ||
| ≥5 cm | 45.12 ± 2.25 | 40.71–49.53 | 46.34 ± 2.16 | 42.11–50.56 | ||
| TNM stage | <0.001 | <0.001 | ||||
| I | 55.49 ± 2.66 | 50.27–60.71 | 55.77 ± 2.58 | 50.71–60.82 | ||
| II | 54.44 ± 1.73 | 51.06–57.83 | 54.99 ± 1.62 | 51.81–58.16 | ||
| III | 33.52 ± 2.42 | 28.77–38.27 | 35.82 ± 2.43 | 31.06–40.59 | ||
| IV | 27.43 ± 6.19 | 15.29–39.56 | 28.19 ± 6.04 | 16.36–40.02 | ||
| Differentiation | <0.001 | <0.001 | ||||
| Well | 54.44 ± 2.17 | 50.19–58.69 | 55.13 ± 2.00 | 51.20–59.05 | ||
| Moderate | 49.47 ± 2.03 | 45.49–53.46 | 50.83 ± 1.88 | 47.14–54.51 | ||
| Poor | 31.15 ± 3.32 | 24.65–37.65 | 32.12 ± 3.22 | 25.81–38.43 | ||
| Infiltrate depth | <0.001 | <0.001 | ||||
| T1 + T2 | 53.80 ± 2.19 | 49.50–58.10 | 53.99 ± 2.13 | 49.81–58.17 | ||
| T3 + T4 | 40.74 ± 2.23 | 36.37–45.10 | 42.36 ± 2.16 | 38.12–46.60 | ||
| Lymphovascular invasion | <0.001 | <0.001 | ||||
| No | 57.04 ± 1.30 | 54.49–59.60 | 57.19 ± 1.25 | 54.73–59.65 | ||
| Yes | 31.90 ± 2.25 | 27.50–36.30 | 34.10 ± 2.29 | 29.61–38.60 | ||
| LNM | <0.001 | <0.001 | ||||
| No | 52.19 ± 1.74 | 48.79–55.59 | 53.02 ± 1.65 | 49.78–56.26 | ||
| Yes | 34.28 ± 2.85 | 28.69–39.87 | 35.78 ± 2.77 | 30.35–41.22 | ||
| Tumor location | 0.090 | 0.067 | ||||
| Rectum | 43.48 ± 2.35 | 38.87–48.09 | 44.86 ± 2.25 | 40.45–49.27 | ||
| Colon | 48.48 ± 2.46 | 43.66–53.29 | 49.19 ± 2.39 | 44.51–53.87 | ||
| PIWIL1 expression | 0.002 | 0.003 | ||||
| Low | 52.90 ± 1.83 | 49.31–56.50 | 53.53 ± 1.72 | 50.16–56.90 | ||
| High | 40.77 ± 2.45 | 35.97–45.57 | 42.14 ± 2.38 | 37.48–46.81 | ||
OS: overall survival; DFS: disease-free survival; SE: standard error; CI: confidence interval; LNM: lymph node metastasis; TNM: tumor node metastasis; alog-rank test.