Figure 1.
Relationship between different morphologic parameters and the presence of a clonal abnormality in Fanconi anemia (FA). The most reliable morphologic criteria for a diagnosis of myelodysplastic syndrome in FA are increased blasts and dysgranulopoiesis (DysGran), followed by dysmegakaryopoiesis (DysMeg) and increased ringed sideroblasts (Rings). Dyserythropoiesis (DysEryth) does not correlate with the presence of clonal abnormalities.