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. Author manuscript; available in PMC: 2018 Apr 20.
Published in final edited form as: Cell Chem Biol. 2017 Apr 6;24(4):507–514.e4. doi: 10.1016/j.chembiol.2017.03.009

Figure 5. Apoptosis and pyroptosis interplay in monocytes and macrophages.

Figure 5

Schematic depicting the bidirectional crosstalk between the apoptotic and pyroptotic cell death pathways in monocytes and macrophages. The dashed red arrow indicates that caspase-1 activates caspase-3/7 in cells, but that it is not yet definitively established if this is due to direct or indirect cleavage in vivo.