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Relative proportion of evolutionary events leading to observed virus:host associations for CoVs in bats. Cophylogenetic reconstructions were used to identify each event (Supplementary Fig. S1: Panels A–D), and significance evaluated by region. Across all regions, host switching was the dominant evolutionary event (Panel A). When separated by region, host switching remained dominant in Africa (Panel B) and Asia (Panel C), but not in Latin America (Panel D).
