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. Author manuscript; available in PMC: 2017 Jun 12.
Published in final edited form as: Pharmacol Biochem Behav. 2015 Dec 15;142:48–55. doi: 10.1016/j.pbb.2015.12.007

Figure 3. Event records from representative subjects under PR and FR schedules.

Figure 3

Panel A shows the cumulative event records during PR responding after EX4 pretreatment from one representative animal. The blue, green, pink and yellow lines represent cumulative lever presses from sessions after saline, 0.6, 1.2 and 2.4 μg/kg pretreatments, respectively. The red dot indicates when 0.1 g of SVS was delivered. Panel B shows the first two minutes of responding from the sessions shown in A. Panel C and D show are representative event records demonstrating the two patterns generally observed after EX4 treatment, in which responding ended prematurely (panel C) or the responding was fragmented during the session. In both PR and FR event records the 0.3 μg/kg dose has not been shown to increase clarity of the figures, as this dose did not significantly alter responding and the cumulative even records were very similar to saline.