Table 2.
Multivariable-adjusted clinical correlates of left ventricular strain measures*
| Predictor variables | Longitudinal strain, %
|
Circumferential strain, %
|
||
|---|---|---|---|---|
| Estimated β (SE) | P-value | Estimated β (SE) | P-value | |
| Age, years | −0.42 (0.12) | 0.0006 | ||
| Female gender | −1.92 (0.13) | <0.0001 | −2.87 (0.24) | <0.0001 |
| Body mass index, kg/m2 | ||||
| SBP, mmHg | ||||
| DBP, mmHg | 0.20 (0.06) | 0.002 | ||
| Antihypertensive therapy | −1.07 (0.25) | <0.0001 | ||
| Diabetes | 0.70 (0.18) | 0.0001 | ||
| Total/HDL cholesterol ratio | 0.34 (0.06) | <0.0001 | ||
| Log triglycerides | ||||
| Current smoker | ||||
| Heart rate, b.p.m. | 0.76 (0.06) | <0.0001 | 1.25 (0.12) | <0.0001 |
| Prevalent CVD | 1.69 (0.17) | <0.0001 | 2.75 (0.35) | <0.0001 |
| Log C-reactive protein | ||||
| Model R2 | 0.190 | 0.115 | ||
CVD, cardiovascular disease; DBP, diastolic blood pressure; SBP, systolic blood pressure.
*
In multivariable analyses, covariates included in model selection were determined using the Schwarz Bayesian criterion. Beta coefficients represent the estimated change in the dependent variable (strain measure) per 1 – SD change in the independent (continuous) variable or presence vs. absence of the independent (categorical) variable.