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. 2017 May 24;51(1):128–144. doi: 10.3892/ijo.2017.4019

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Copyright: © Abeni et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Examples of molecular signaling pathways found enriched by WebGestalt. (A) MAPK signaling pathway. (B) IL-3 signaling pathway. The tables report the genes whose level of methylation was changed after the treatment of HA22T/VGH with sorafenib. Negative and positive MAT-scores indicate a given gene hypomethylated or hypermethylated, respectively. The column 'OG/TSG' indicates the presence of evidence in published reports that a given gene acts as oncogene (OG), tumor suppressor gene (TSG) or neither (−). Histograms indicate the number of OG or TSG that were hypomethylated or hypermethylated in our study.