Table VI.
Genes validated by quantitative COBRA assay and direct bisulfite sequencing.
| Gene | Chr | DMR start | DMR end | DMR length | No. of CpG in DMR | CpG observed/CpG expected | P-value | MAT score | DMR position |
|---|---|---|---|---|---|---|---|---|---|
| BIRC3 | chr11 | 101693878 | 101695822 | 1944 | 25 | 0.27 | 1.29E-04 | +12.10 | Gene body: Intronic |
| FOXO3 | chr 6 | 108987593 | 108990713 | 3120 | 312 | 0.87 | 2.77E-04 | −10.33 | Promoter region |
| MAPK3 | chr16 | 30037080 | 30039335 | 2255 | 29 | 0.21 | 1.11E-04 | +12.42 | Gene body: Intronic and exonic |
| SMAD2 | chr18 | 43709687 | 43712269 | 2582 | 228 | 0.94 | 1.66E-04 | −10.86 | Promoter region |
| TSC2 | chr16 | 2043747 | 2047150 | 3403 | 121 | 0.40 | 3.69E-05 | −13.04 | Gene body: Intronic and exonic |