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. 2017 May 11;51(1):104–114. doi: 10.3892/ijo.2017.3996

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Copyright: © Lindsten et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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(A) Effects of conditioned media (CM) from macrophages of M1 and M2 phenotype on the proliferation of T47D breast cancer cells. Results are expressed as percentage of mean value ± standard deviation. Asterisks indicate significant differences compared to the untreated control (100%) (^*p<0.05, ^**p<0.01, ^***p<0.001). (B) Immunoreactivity for the proliferation marker Ki67 in T47D breast cancer cell line. Representative examples of the effect from treatment with conditioned media (CM) from macrophages (b) of M1 or (c) M2 phenotype demonstrating a reduced Ki67 protein immunoreactivity compared with (a) untreated T47D cells (×400 magnification, calibration bar is 50 µm in all micrographs).