Table V.
mRNA expression levels in macrophages of M1 and M2 phenotypes in comparison to M0.
| Target mRNA | M0 0 h | M1 0 h | M2 0 h | M0 48 h | M1 48 h | M2 48 h |
|---|---|---|---|---|---|---|
| IL6 | 1 | U 190-foldb | U 10-fold | ND | ND | ND |
| IL8 | 1 | U 1700-foldc | D 2-folda | 1 | U 26-foldc | U 2-folda |
| IL10 | 1 | D 5-folda | 1 | 1 | U 5-fold | 1 |
| IL12 | 1 | U 5-foldc | 1 | D 2-fold | 1 | D 3-fold |
| CCL2 | 1 | D 2-fold | 1 | D 2-fold | 1 | D 8-fold |
| CCL17 | 1 | D 10-fold | U 4-fold | D 5-fold | ND | U 3-fold |
| CCL18 | 1 | U 26-fold | U 115-fold | D 2-fold | U 30-folda | U 30-fold |
| CXCL9 | 1 | U 14,000-foldc | 1 | D 5-fold | U 190-folda | D 3-fold |
| TNF-α | 1 | U 95-foldc | 1 | D 2-fold | U 7-folda | D 5-folda |
| NFκB | 1 | U 9-foldb | 1 | 1 | U 4-folda | 1 |
a
p<0.05,
b
p<0.01,
c
p<0.001. ND, not detected; U, upregulation; D, downregulation. 0 h indicate differentiated macrophages; 48 h indicate macrophages 48 h post-differentiation.