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. 2017 Jun 12;12(6):e0179131. doi: 10.1371/journal.pone.0179131

Fig 1. Drug delivery model overview.

Fig 1

Intravascular temperature-dependent release of Dox from TSL, uptake by interstitium (EES), and cell uptake are simulated. Local temperature and perfusion are fed into the drug delivery model from the heat transfer model.