Table 2.
MRI was performed at rest and during dobutamine stress in 15 patients with PH and five younger volunteers. Values are median (interquartile range).
| PH patients |
Younger Volunteers |
|||
|---|---|---|---|---|
| Rest | Stress | Rest | Stress | |
| Pulmonary artery | ||||
| AMAX (cm2) | 9.3 (7.1–11.0) | 9.6 (7.2–11.5)* | 6.8 (6.0–7.9)† | 7.1 (6.5–8.0) |
| AMIN (cm2) | 8.2 (5.9–9.9) | 8.3 (6.0–10.7)** | 5.2 (3.6–5.7)‡ | 4.1 (3.6–5.0) |
| RAC (%) | 12.6 (9.4–19.2) | 11.0 (9.2–16.5) | 43.6 (33.1–74.6)‡ | 67.5 (29.4–85.4)# |
| Right ventricle | ||||
| SVI (mL/m2) | 23 (17–37) | 26 (22–34) | 47 (44–49)‡ | 52 (49–58)# |
| EDVI (mL/m2) | 98 (68–113) | 81 (60–108) | 67 (61–87) | 64 (58–76) |
| ESVI (mL/m2) | 56 (38–73) | 42 (24–54)* | 29 (23–42)† | 11 (9–22)# |
| EF (%) | 34 (18–43) | 40 (23–46)* | 67 (52–81)‡ | 85 (82–93)# |
| CI (L/min/m2) | 1.9 (1.5–2.4) | 2.8 (2.4–3.5)** | 2.9 (2.4–2.9) | 5.2 (4.4–5.9)# |
| HR (bpm) | 75 (65–87) | 109 (88–121)** | 60 (50–66) | 87 (84–94)# |
| η'vv | 0.6 (0.2–0.8) | 0.8 (0.4–1.3)** | 1.7 (1.0–2.0)‡ | 4.9 (2.9–5.9)# |
AMAX, maximum PA area; AMIN, minimum PA area; RAC, Relative area change; RV, right ventricle; LV, left ventricle; SVI, stroke volume index; EDVI, end-diastolic volume index; ESVI, end-systolic volume index; EF, ejection fraction; CI, Cardiac Index; HR, heart rate; η'vv, RV SV/ESV. *P < 0.05. **P < 0.01 (PH Stress vs. Rest). †P < 0.05. ‡P < 0.01 (PH vs. Volunteers at rest). #P < 0.05 (Volunteers Stress vs. Rest).