Table 1.

Comparison of microCT 3D morphometry parameter values for each lobe from the right lungs of control and SU/hyp animals.

	Control				SU/Hyp
	Superior Lobe 1	Middle Lobe 2	Inferior Lobe 3	Accessory Lobe 4	Superior Lobe 1	Middle Lobe 2	Inferior Lobe 3	Accessory Lobe 4
Vascular volume/ tissue volume* (mm3/mm3)	0.333 (0.27–0.40)	0.304 (0.28–0.42)	0.347 (0.27–0.43)	0.373 (0.29–0.43)	0.236 (0.23–0.34)	0.261 (0.21–0.32)	0.233 (0.21–0.30)	0.273 (0.25–0.33)
Connectivity density† (1/mm3)	51.8 (25–60)	18.9 (16–29)	44.7 (29–54)	21.5 (14–24)	41.3 (23–60)	31.5 (17–38)	22.0 (15–42)	24.1 (16–33)
Vascular number‡ (1/mm)	3.32 (3.0–3.7)	2.39 (2.3–2.7)	2.71 (2.4–2.9)	2.68 (2.6–2.8)	3.11 (2.3–3.2)	2.75 (2.5–3.0)	2.27 (2.2–2.5)	2.55 (2.2–2.7)
Vascular lumen diameter§ (mm)	0.305 (0.27–0.40)	0.507 (0.49–0.59)	0.550 (0.46–0.64)	0.552 (0.52–0.59)	0.356 (0.30–0.38)	0.419 (0.35–0.51)	0.594 (0.55–0.62)	0.482 (0.44–0.55)
Vascular separation** (mm)	0.264 (0.25–0.29)	0.350 (0.21–0.42)	0.271 (0.26–0.37)	0.287 (0.23–0.34)	0.346 (0.29–0.44)	0.338 (0.28–0.41)	0.384 (0.35–0.41)	0.365 (0.33–0.42)
Vascular surface area/ vascular volume†† (1/mm)	14.9 (14–19)	12.3 (12–13)	13.5 (12–15)	11.6 (11–12)	15.4 (14–17)	14.5 (14–16)	14.7 (13–16)	13.5 (13–15)

Values are presented as median (25–75%).

^*Relative volume of vasculature in the lung lobe.

^†Branching of vasculature, higher number signifies more vascular branching normalized by lobe volume.

^‡Number of continuous blood vessels at any point.

^§Blood vessel lumen diameter.

^**Distance between the centers of adjacent blood vessels.

^††Relative surface area of the blood vessels related to total vascular volume.