Table 1.
Disease course of single PET-CT positive sites after first and second adoptive transfer of HLA-A*02:01/CHM1319 TCR transgenic T cells compared with reference PET-CT before therapy (Patient #2).
| After first adoptive transfer |
After second adoptive transfer |
|||||
|---|---|---|---|---|---|---|
| Progressive sites | New metastases | Regressive sites | Progressive sites | New metastases | Regressive sites | |
| Lower extremity | 1 | 1 | 0 | 1 | 7 | 1 |
| Pelvis | 3 | 1 | 0 | 1 | 2 | 4 |
| Upper extremity | 0 | 0 | 0 | 0 | 1 | 0 |
| Lungs | approx. 50 | approx. 30 | 0 | >50 | >50 | 0 |
| Skull | 0 | 0 | 0 | 0 | 0 | 1 |