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. 2017 Mar 31;6(5):e1310359. doi: 10.1080/2162402X.2017.1310359

Figure 4.

Figure 4.

Correlation of autoantibodies to ECH1 and HNRNPA2B1 with tumor size and lymph node number in lung cancer patients in validation set 2 group 3. 4A–4D: Box and Whisker plots for serum levels of anti-ECH1 in different tumor size (4A) and lymph node number (4C), and anti-HNRNPA2B1 levels in different tumor size (4B) and lymph node number (4D). The line within the box marks the median, and the 25th and 75th percentiles are presented by the edges of the area, which is known as inter-quartile (IQR). The bars indicate 1.5 times of the IQR from upper or lower percentiles. Mann–Whitney test was used to compare the difference of antibody levels in different tumor size and lymph node numbers. 4E–4H: Scatter graph for serum levels of anti-ECH1 in tumor size (4E) and lymph node number (4G), and anti-HNRNPA2B1 levels in tumor size (4F) and lymph node number (4H). Spearman's rank-order test was used to evaluate the correlation of autoantibody level with tumor size and lymph node numbers. LM: lymph node metastasis number.