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. 2017 May 12;18(4):684–689. doi: 10.5811/westjem.2017.3.33607

Table 2.

Laboratory risk indicatory for necrotizing fasciitis (LRINEC) score for necrotizing fasciitis and cellulitis by diabetes status.

Diabetes subgroup Non-diabetes subgroup


NF (n=16) Cellulitis (n=474) p-value NF (n=31) Cellulitis (n=474) p-value
LRINEC groups 0.0012 <.0001
High risk: LRINEC ≥8 9 (56.3%) 12 (2.5%) 7 (22.6%) 28 (5.9%)
Moderate risk: LRINEC 6 and 7 0 (0%) 26 (5.5%) 1 (3.2%) 36 (7.6%)
Low risk: LRINEC ≤5 7 (43.8%) 436 (92%) 23 (74.2%) 410 (86.5%)
Missing = 41 Missing = 47
WBC (*1000 per mm3) 18.13 ± 10.57 9.76 ± 4.94 <.0001 18.22 ± 6.33 9.27 ± 5.8 <.0001
Hemoglobin (g/dL) 13.11 ± 2.33 12.93 ± 2.03 0.4827 12.38 ± 2.35 12.21 ± 2.32 0.6003
Sodium (mmol/L) 133.08 ± 5.35 138.04 ± 3.47 <.0001 129.65 ± 6.47 137.33 ± 4.15 <.0001
Creatinine (umol/L) 159.27 ± 158.23 77.04 ± 77.23 <.0001 159.15 ± 158.38 106.36 ± 105.78 0.0225
Glucose (mmol/L) 7.54 ± 3.76 6.42 ± 2.15 0.013 22.2 ± 12.62 12.12 ± 6.14 <.0001
CRP (mg/dL) 167.64 ± 153.64 62.6 ± 87.92 0.0194 200.4 ± 199.61 60.75 ± 96.17 0.0002
Age, years 45.93 ± 14.16 46.46 ± 14.66 0.7725 49.5 ± 10.53 54.21 ± 11.61 0.0053

LRINEC, laboratory risk indicator for necrotizing fasciitis; NF, necrotizing Fasciitis; WBC, white blood cell; CRP, c-reactive protein.

To change the creatinine from umol/L to mg/dL, use the formula mg/dL=88.4*umol/L.

To change glucose from mmol/l to mg/dL, use the formula mg/dL=0.055 mmol/L.

To change CPR from mg/dL to mg/L, use the formula mg/L=0.1* mg/dL.