Table 2.
Strategy | Cumulative Lifetime Probability, % | Cost, $ | Life-Years† | QALYs | Incremental Cost, $ | Incremental QALYs | ICER, $/QALY‡ | |
---|---|---|---|---|---|---|---|---|
Hip Fracture | Death Due to Hip Fracture | |||||||
No test and no alendronate therapy | 12.6 | 0.43 | 75 474 | 10.9965 | 6.5930 | Reference§ | Reference§ | Reference§ |
Test and selective alendronate therapy | 12.0 | 0.40 | 75 652 | 10.9971 | 6.5957 | 178 | 0.0027 | 66 800 |
No test and universal alendronate therapy | 9.9 | 0.33 | 77 153 | 10.9991 | 6.6041 | 1501 | 0.0084 | 178 700 |
ICER = incremental cost-effectiveness ratio; QALY = quality-adjusted life-year.
The strategy was considered cost-effective if its ICER was less than $100 000 per QALY gained (32, 63).
Undiscounted results.
ICER was measured by cost per QALY gained.
The no test–no alendronate strategy was the reference strategy because it was the least costly, viable (nondominated) option.