Figure 6.

Representative images of pre-vascularized pulp-like tissue construct. (A) Longitudinal and (B) cross-sectional views of GelMA hydrogels loaded with green fluorescent microparticles showing the fabricated microchannel after being perfused with a red fluorescent microparticle solution. The channels cross the entire length of the root. (C,D) Photographs of GelMA hydrogels from longitudinal and occlusal perspectives inside a full-length root fragment. Root fragments were stabilized prior to hydrogel loading and microchannel fabrication, and were separated to retrieve the constructs and illustrate the position of the hydrogel inside the tooth. Microchannels were perfused with red food dye.