Table 1.
IC50 values and slopes of the rocuronium dose-response curves for the normal, DIII (grade III), and DIV (grade IV) facial nerve injury groups.
| Normal | Facial nerve injury group | |||||||
|---|---|---|---|---|---|---|---|---|
| Day 1 | Day 3 | Day 7 | Day 14 | Day 30 | Day 60 | Day 90 | ||
| DIII | ||||||||
| IC50 | 7.28 (7.10–7.46) | 7.34 (6.88–7.82) | 7.59 (7.15–8.05) | 7.95 (7.55–8.38) | 8.16* (7.80–8.55) | 7.28 (6.91–7.68) | 7.26 (6.82–7.73) | 7.47 (7.04–7.93) |
| Hillslope | 4.15 ± 0.19 | 3.98 ± 0.43 | 4.01 ± 0.39 | 4.47 ± 0.39 | 4.62 ± 0.35 | 4.46 ± 0.44 | 3.83 ± 0.40 | 4.06 ± 0.40 |
| DIV | ||||||||
| IC50 | 7.21 (6.82–7.62) | 7.37 (6.99–7.77) | 10.11*#▴☆Δ★ (9.60–10.65) | 9.84*#▴☆Δ★ (9.29–10.43) | 8.33*# (7.90–8.79) | 7.62 (7.23–8.02) | 7.54 (7.04–8.09) | |
| Hillslope | 4.26 ± 0.43 | 4.18 ± 0.38 | 5.19 ± 0.61*#▴★ | 4.78 ± 0.54 | 4.74 ± 0.43 | 4.44 ± 0.40 | 3.96 ± 0.45 | |
IC50 values and slopes at the IC50 are means with 95% confidence intervals and means ± standard deviation, respectively. *P < 0.05 vs. normal; #P < 0.05 vs. day 1; ▴P < 0.05 vs. day 3; ☆P < 0.05 vs. day 30; ΔP < 0.05 vs. day 60; ★P < 0.05 vs. day 90.