Table 2.

Characteristics of in-hospital survivors and deceased

Characteristics	In-hospital survivors (n = 370)	In-hospital deceased (n = 261)	p
Demographics
Age (years)	58.5 [47–67.75]	63 [52–71]	0.01
Male gender	240 (64.9%)	166 (63.6%)	0.81
Comorbid illnesses
Performance status 3–4	61 (16.5%)	77 (29.5%)	0.0001
Charlson comorbidity index	4 [2–5]	4 [3–6]	0.008
Underlying malignancy			0.90
Lymphoid disease	179 (48.4%)	131 (50.2%)
Myeloid disease	121 (32.7%)	83 (31.8%)
Time between diagnosis and ICU admission (days)	91 [14; 444]	90 [11; 396]	0.58
Hematopoietic stem cell transplantation			0.04
Autologous	52 (14.1%)	24 (9.2%)
Allogeneic	55 (14.9%)	55 (21.1%)
Malignancy status			0.019
Newly diagnosed	106 (28.7%)	84 (32.2%)
Partial/complete remission	116 (31.4%)	53 (21.4%)
Time between hospital and ICU admissions (days)	4 [0–16]	9 [1–25]	<0.0001
ICU admission characteristics
SOFA score	6 [4–8]	8 [5–11.75]	<0.0001
Neutropenia	125 (33.8%)	104 (39.9%)	0.14
Lactate (mmol/L)	1.9 (1.125–3.575)	2.4 [1.6–5.6]	0.0001
Hemoglobin level (g/dL)
Day 1	9.2 [8–10.7]	8.9 [7.8–10.2]	0.02
Day 2	9.2 [8.3–10.2]	9.1 [8.3–10]	0.33
Day 3	9 [8.1–10]	8.9 [8.2–9.975]	0.88
Day 7	8.8 [8.1–9.8]	8.8 [8.3–9.95]	0.53
RBC transfusion
Day 1 and/or 2	103 (27.8%)	107 (41%)	0.0008
Day 3	42 (12.4%)	39 (17.3%)	0.13
Day 7	16 (10.6%)	21 (16.7%)	0.19
Source of infection
Pneumonia	190 (51.4%)	68 (64.3%)	0.002
Abdominal	69 (18.7%)	34 (13.0%)	0.076
Urinary tract	21 (5.7%)	15 (5.8%)	1.00
Catheter-related	21 (5.7%)	7 (2.7%)	0.11
Pathogens
Gram-negative bacteria	101 (27.3%)	74 (28.4%)	0.84
Gram-positive bacteria	56 (15.1%)	25 (9.6%)	0.053
Aspergillus	27 (7.3%)	42 (16.1%)	0.0008
Pneumocystis	17 (4.6%)	5 (1.9%)	0.11
Life-supporting interventions
Vasopressive drugs	184 (49.7%)	206 (78.9%)	<0.0001
Invasive ventilation	124 (33.5%)	197 (75.5)	<0.0001
Renal replacement therapy	56 (15.4%)	98 (38.7%)	<0.0001

ICU intensive care unit, RBC red blood cell, SOFA sequential organ failure assessment