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. 2017 Jun 13;8:684. doi: 10.3389/fimmu.2017.00684

Figure 9.

Figure 9

Cytokine–cytokine receptor interaction pathway. Genes found to be differentially up- (red) and downregulated (green) in dendritic cells (DCs) stimulated with the mix of PLGA-chCPAp-MPLA, PLGA-chH1p-MPLA, and PLGA-KMP-11p-MPLA nanoformulations (mix B) compared to unstimulated DCs. “Cytokine-cytokine receptor interaction” (mmu04060) KEGG pathway was adapted in order to place emphasis specifically on the deregulated genes (p < 0.05, 1.5-fold upregulation or downregulation), as dictated by the microarray experiments. Pathview package was utilized to color nodes of differentially expressed genes.