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. 2017 Jun 13;8:416. doi: 10.3389/fphys.2017.00416

Table 4.

Relation matrix.

δFOXO+ |δFOXO-| δPI3K+ |δPI3K-| δmTORC1+ δmTORC1- δmTORC2+ |δmTORC2-| δAkt+ |δAkt-|
δFOXO+ =
|δFOXO-| ≤, ≥ =
|δPI3K-| ≤, ≥ ≤, ≥ =
δPI3K+ ≤, ≥ ≤, ≥ ≤, ≥ =
δmTORC1+ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ =
|δmTORC1-| ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ =
δmTORC2+ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ =
|δmTORC2-| ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ =
δAkt+ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ =
|δAkt-| ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ ≤, ≥ =

Relation matrix of the selected cycle that shows the pairwise relationships of delays of the entities FOXO, PI3K, mTORC1, mTORC2 and Akt.