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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Ultramicroscopy. 2017 Mar 1;180:180–187. doi: 10.1016/j.ultramic.2017.01.002

Figure 7.

Figure 7

EFTEM spectrum-image from plastic sections of hybrid nanocomplexes containing heparin, protamine, and ferumoxytol, which are being used for magnetic labeling of stem cells. (a) Fe L2,3 edge image; (b) overlay of Fe L2,3 edge image (red), S L2,3 edge image (blue) and N K edge image (green) shows that the iron-containing ferumoxytol nanoparticles surround a soft core composed of sulfur-containing heparin and nitrogen-containing protamine. The two components in the core co-localize due to association between the negatively charged heparin and the positively charged protamine. From L.H. Bryant et al. [38].