Table 1.

Best-fit estimates of dose–response curve parameters of EIs

Data				Fits
Compound	Cell line	HCV genotype	Ref.	m	IC50	R2
EI-1	Huh-H1	1b	(4)	1.59	1.75 × 10−2 μM	0.997
PRO0371155	Hep3B	1a	(5)	1.13	7.67 × 10−4 μM	0.951
Dasatinib	Huh 7.5.1	2a (J6)	(6)	0.55	0.42 μM	0.965
Erlotinib	Huh 7.5.1	2a (J6)	(6)	0.55	0.24 μM	0.976
ITX5061	PHH	1b (HCV-J)	(7)	0.36	6.28 × 10−3 µM	0.88
MAb 9/27	Huh 7	1a	(8)	1.57	0.31 μg⋅mL−1	0.995
MAb 1/39	Huh 7	1a	(8)	0.87	1.1 μg⋅mL−1	0.971
MAb JS81	Huh 7	N/A	(9)	1.58	4.42 × 10−2 μg⋅mL−1	0.923
MAb 1D6	Huh 7	N/A	(9)	1.08	12.02 μg⋅mL−1	0.994
Civacir	Huh 7.5.1	2a	(10)	0.61	40.36 μg⋅mL−1	0.977

N/A, not available; PHH, primary human hepatocytes.