Fig. S1.
Expression of HDAC1 is elevated in patients with schizophrenia. (A) qPCR analysis from the human prefrontal cortex revealed a highly significant up-regulation of Hdac1 mRNA in patients with schizophrenia (n = 10) compared with control individuals (n = 11; **P = 0.009, unpaired t test). Levels of other class I HDACs were not affected. (B) Immunoblot analysis confirmed elevated HDAC1 protein levels in the prefrontal cortex from patients with schizophrenia and control individuals (n = 9 per group; *P = 0.0128, unpaired t test). Error bars indicate SEM. A.U., arbitrary units; Rel., relative.