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. 2017 May 22;114(23):E4648–E4657. doi: 10.1073/pnas.1704698114

Fig. S3.

Fig. S3.

SEC profiles of recombinant human αSyn monomers and of soluble αSyn assemblies present in TgI2.2, WT, and SCNA-null forebrain tissues. (A) Representative Western blot (WB) profile of recombinant human αSyn monomers detected in SEC fractions. Blue arrows indicate the elution of used globular standards. The Left Inset corresponds the nonsegregated material. Samples of interest were separated onto two separate 12-well gels in parallel. (B–D) Representative Western blot profile of soluble αSyn molecules detected in SEC fractions from forebrain tissue of 11-mo-old TgI2.2 (B), WT (C), and SNCA-null (D) mice. Of total proteins from the IC-enriched fraction, 250 μg was injected. The Left Inset in B corresponds with the nonsegregated material. Samples of interest were separated onto two separate 12-well gels in parallel.